Reema founded Green Sands Equity in June 2016 and is currently based in GSE's San Francisco office.  She is responsible for all aspects of the firm's investment strategy, team and operations across GSE's global network. She also specializes in strategic advisory for governments in their branding for Foreign Direct Investment. GSE's vast political and diplomatic network makes GSE one of the top strategy advisors to governments.

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Reema is the recipient of the 2026 Ellis Island Medal of Honor for her contributions to the United States. Since 2018, Reema has been an ambassador to the United Nations on behalf of Royal Academy of Science International Trust. She is a trustee of the SETI Institute and Chairwoman of their Endowment. The SETI Institute is a scientific organization, substantially funded by NASA grants, dedicated to investigating the nature of the universe and the prevalence of life beyond Earth.

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In philanthropic endeavors, Reema endowed the Green Sands AI Fund at MIT. At SLAC Stanford, she endows the SAGE program. Annually, she awards the "Green Sands Prize” to leaders who have made a profound impact on society. Recipients have included NASA astrophysicist Dr. Jill Tarter, 43rd Treasurer of the United States, Rosie Rios, COO of Space X, Gwynne Shotwell, and NIH Lead under Dr. Fauci, Kizzmekia Corbett. Reema lectures at Stanford Graduate School of Business and Berkley Haas School of Business on Investment, AI, and Entrepreneurship.